- Teppo L N Järvinen, orthopaedic resident1,
- Harri Sievänen, head2,
- Karim M Khan, associate professor3,
- Ari Heinonen, professor4,
- Pekka Kannus, professor12
- 1Division of Orthopaedics and Traumatology, Department of Trauma, Musculoskeletal Surgery and Rehabilitation, Tampere University Hospital, 33 520 Tampere, Finland
- 2Bone Research Group, UKK-Institute, Tampere, Finland
- 3Department of Family Practice and Centre for Hip Health, University of British Columbia, Vancouver, British Columbia, Canada
- 4Department of Health Sciences, University of Jyväskylä, Jyväskylä, Finland
- Correspondence to: T L N Järvinen teppo.jarvinen{at}uta.fi
- Accepted 11 November 2007
Fractures are a rapidly growing problem among older people. Hip fractures alone cost over $20bn (£10bn; €13bn) in the United States in 1997.1 Any intervention that may reduce the risk of fracture at either the individual or population level therefore warrants critical appraisal. The mainstay of current strategies to prevent fractures is to screen for osteoporosis by bone densitometry and then treat people with low bone density with antiresorptive or other bone-specific drugs.234 However, the strongest single risk factor for fracture is falling and not osteoporosis.5 6 Despite this fact, few general practitioners will have assessed the risk of falling among their elderly patients or even know how to do it.7 Risk of falling is also completely overlooked in many important publications on preventing fractures.4 We argue that a change of approach is needed.
Predictive value of bone density measurements
Bone densitometry does not give reliable estimates of a person’s true bone mineral density. The planar scanning principle of dual energy x ray absorptiometry, and assumptions in processing the scan data, can underestimate or overestimate bone mineral density by 20-50%.8 This means that a patient with a bone mineral density T score of −1.5 may have a true value between −3.0 and 0−that is, a range from clear osteoporosis to normal. Thus, not surprisingly, bone mineral density is a poor predictor of fracture in individuals (fig 1⇓). In addition, when different scanners are used on the same patients, the proportion of patients diagnosed with osteoporosis varies from 6% up to 15%.9
Fig 1 Femoral neck bone mineral density versus age at time of fall in people who …
Sign in
Personal subscribers, sign in here:
Article access
Article access for 1 day
Purchase this article for £20 $30 €32*
The PDF version can be downloaded as your personal record
CiteULike
Connotea
Del.icio.us
Digg
Facebook
Reddit
Technorati
Twitter
Stumbleupon
Rapid responses
Latest Responses
The decline in the breast cancer incidence is 1.2% and it is not significant.
Published 10 February 2012
'twas ever thus
Published 10 February 2012
The value of historic human remains
Published 10 February 2012
In Praise of British Literature
Published 10 February 2012
Is real shared decision making possible?
Published 10 February 2012
Most responses
Does anyone understand the government’s plan for the NHS? (17 responses)
Published 17 Jan 2012
Bad medicine: medical nutrition (15 responses)
Published 18 Jan 2012
Shared decision making: really putting patients at the centre of healthcare (7 responses)
Published 27 Jan 2012
Why legislation is necessary for my health reforms (7 responses)
Published 1 Feb 2012
Search for evidence goes on (5 responses)
Published 17 Jan 2012