Letters Atrial fibrillation

Rate control and digoxin

BMJ 2007; 335 doi: https://doi.org/10.1136/bmj.39416.442731.BE (Published 06 December 2007) Cite this as: BMJ 2007;335:1169
  1. Gregory Y H Lip, clinical adviser,
  2. Michael Rudolf, chair
  3. Guideline development group for the NICE clinical guideline for the management of atrial fibrillation
  1. 1Clinical Guideline Group, NICE, London WC1V 6NA
  1. g.y.h.lip{at}bham.ac.uk

    Nikolaidou and Channer’s editorial suggests that no single definition of ideal control of heart rate in chronic atrial fibrillation (AF) exists,1 but current recommendations are between 60 and 90 beats/min at rest and between 90 and 180 beats/min during moderate exercise.2 However, no controlled clinical trials have validated these target rates for preventing all-cause cardiovascular morbidity or mortality, and the best method …

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