Be careful with claims that sex modifies genetic risk of diseaseBMJ 2007; 335 doi: http://dx.doi.org/10.1136/bmj.335.7618.473-a (Published 06 September 2007) Cite this as: BMJ 2007;335:473
Experience from observational studies and randomised trials teaches us that sex was often misinterpreted as a modifying factor in the risk of disease or response to treatment. For example, on the basis of one underpowered subgroup analysis, we believed for more than a decade that …
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