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Evidence for guidelines often lacks external validity

BMJ 2007; 335 doi: http://dx.doi.org/10.1136/bmj.335.7618.472-a (Published 06 September 2007) Cite this as: BMJ 2007;335:472

Guidelines for clinical practice have proliferated recently and most say they are backed up by research findings. A study of 338 recommendations from nine guidelines for management of cardiovascular risk found, however, that fewer than one third were supported by high …

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