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Eprodisate slows kidney decline in amyloid A amyloidosis

BMJ 2007; 334 doi: https://doi.org/10.1136/bmj.334.7606.1245-a (Published 14 June 2007) Cite this as: BMJ 2007;334:1245

Amyloid A amyloidosis is a rare complication of chronic inflammatory diseases and chronic infections. In this condition, a proteolytic fragment of serum amyloid A protein—an acute phase reactant produced in the liver—is deposited extracellularly in the tissues as insoluble fibrils. Such deposition causes progressive dysfunction of organs and, eventually, death. A new drug, eprodisate, inhibits …

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