Letters Thromboprophylaxis for adults in hospital

Prophylaxis for medical inpatients is not entirely proven

BMJ 2007; 334 doi: http://dx.doi.org/10.1136/bmj.39226.442083.3A (Published 31 May 2007) Cite this as: BMJ 2007;334:1127
  1. Domnick F D'Costa, consultant physician, general medicine and care of the elderly
  1. Royal Wolverhampton Hospitals, Wolverhampton WV10 0QP
  1. Domnick.DCosta{at}rwh-tr.nhs.uk

    I have three concerns with regard to the editorial by Fitzmaurice and Murray.1 Firstly, a recent meta-analysis on anticoagulant prophylaxis to prevent symptomatic venous thromboembolism (VTE) in 19 958 hospitalised medical patients showed only modest benefit.2 The numbers needed to treat were 345 (absolute risk reduction 0.29%) to prevent one pulmonary embolism (PE) and 400 …

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