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Antidepressants ineffective in bipolar depression

BMJ 2007; 334 doi: (Published 03 May 2007) Cite this as: BMJ 2007;334:926

The antidepressants bupropion and paroxetine don't work for patients with major depression associated with bipolar disorder, report researchers from the United States. In the largest trial to date, neither drug helped patients achieve a durable remission when used in conjunction …

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