BMJ 2007; 334 doi: https://doi.org/10.1136/bmj.39143.537940.471 (Published 08 March 2007) Cite this as: BMJ 2007;334:542

One minute you've got restless legs and the next minute you could find yourself becoming a pathological gambler, even if you've never gambled before. As in people with Parkinson's disease treated with dopamine agonists, people with restless legs syndrome who were taking dopaminergic agonists have been reported to develop pathological gambling (Neurology 2007;68:301-3 doi: 10.1212/01.wnl.0000252368.25106.b6). Causation is assumed because the gambling behaviour resolved when the treatment was discontinued.

Forty years ago psychologist Stanley Milgram found that there was an average of six degrees of separation between strangers. Psychologists and other scientists continue to explore the idea that all sorts of large networks can be traversed in a small number of steps. This applies to our inner networks too and runs counter to the views of all those neuroscientists who like to pigeonhole bits of brain into specific specialist …

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