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Poor adherence to drug treatment increases mortality after a heart attack

BMJ 2006; 333 doi: https://doi.org/10.1136/bmj.333.7575.0-e (Published 02 November 2006) Cite this as: BMJ 2006;333:0-e

Research question Does non-adherence to drug treatments affect survival after a heart attack?

Answer Yes. Patients who stop taking their aspirin, β blockers, and statins are more likely to die within a year than patients who continue to take at least one of them

Why did the authors do the study? They wanted to find out how many patients stopped taking their prescribed drugs after a heart attack, when they stopped, and whether this affected their survival. They also wanted to explore the factors associated with non-adherence to treatment.

What did they do? They followed up a cohort of 1521 US men and women who had been treated for myocardial infarction and then …

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