Letter

Test for quinolone resistance in typhoid fever

BMJ 2006; 333 doi: https://doi.org/10.1136/bmj.333.7561.260-b (Published 27 July 2006) Cite this as: BMJ 2006;333:260
  1. Christopher M Parry (cmparry@liv.ac.uk), senior lecturer,
  2. Lilani Karunanayake, consultant,
  3. J Brian S Coulter, senior lecturer, tropical child health,
  4. Nicholas J Beeching, senior lecturer, clinical group
  1. Medical Microbiology and Genitourinary Medicine, University of Liverpool, Liverpool L69 3GA
  2. Medical Microbiology, Teaching Hospital, Kandy, Sri Lanka
  3. Liverpool School of Tropical Medicine, Liverpool L3 5QA

    EDITOR—Bhutta summarised current issues in the diagnosis and treatment of typhoid fever.1 We highlight the need for the use of appropriate laboratory methods to detect clinically significant quinolone resistance.

    Quinolone resistant isolates of Salmonella enterica serovar Typhi have reduced susceptibility to ciprofloxacin, with minimum inhibitory concentrations between 0.1 mg/l and 1 mg/l compared with wild type strains …

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