Oxygen and inhalers

Oxygen

Administering oxygen for chronic obstructive pulmonary disease (COPD) is not without risk and it should be properly prescribed—in terms of flow rate and mode of delivery—like any other drug. Giving high concentrations of oxygen to hypoxaemic patients with hypercapnia can result in individuals losing their hypoxic drive to breathe, with development of CO₂ retention, respiratory acidosis, and even death.

However, in acute and chronic ventilatory failure, oxygen supplementation is essential to maintain adequate delivery of oxyhaemoglobin to organs such as the heart, kidneys, and brain. Many patients who are chronically hypoxic are able to cope satisfactorily with an oxygen saturation of arterial blood of around 90%. However, at saturations below this, the oxygen dissociation curve rapidly steepens, and a sharp fall in oxygenated haemoglobin occurs with reduction in oxygen supply to vital organs.

Oxygen during an exacerbation of COPD

During an exacerbation of COPD, give 24% or 28% oxygen via a Venturi facemask to patients with hypercapnia in order to maintain an oxygen saturation > 90%. In patients without hypercapnia, titrate the oxygen concentration upwards to keep the saturation > 90%. Check arterial blood gases at 30-60 minutes later to check for any rise in CO₂. Nasal cannulas deliver less reliable fractions of inspired oxygen than a facemask but allow patients to communicate, eat, and drink more easily.

A concentrator supplies oxygen to patients without the need for gas cylinders