Rectal quinine for malaria: Authors' reply

doi:10.1136/bmj.332.7551.1216-b

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H Barennes (hubert.barennes@auf.org), epidemiologist,
E Pussard, pharmacologist

Centre Muraz, 01BP390 Bobo-Dioulasso, Burkina Faso
Hôpital du Kremlin Bicêtre, Service de Pharmacologie, France

EDITOR—Hypoglycaemia resulting from quinine induced hyperinsulinaemia is indeed a side effect of quinine treatment. We assumed that the risk of hypoglycaemia is similar after rectal or intramuscular quinine because rectal administration of doses of 16 or 20 mg/kg …