Risks and benefits of omega 3 fats: A few thoughts on systematic review

doi:10.1136/bmj.332.7546.915-a

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Ka He, assistant professor (kahe@northwestern.edu),
Yiqing Song, instructor

Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 North Lake Shore Drive, Suite 1102, Chicago, IL 60611, USA
Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA

EDITOR—Hooper et al's conclusions that omega 3 fats have no effect on total mortality, combined cardiovascular events, or cancer are somewhat misleading.1

Firstly, their null findings could be partly explained by the use of the composite end points. They ignore strong biological evidence for the potentially disease specific effects of omega 3 fat. The underlying hypotheses for this study are not clearly …