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Vitamin D plus calcium prevents falls in older women but not older men

BMJ 2006; 332 doi: https://doi.org/10.1136/bmj.332.7546.0-e (Published 13 April 2006) Cite this as: BMJ 2006;332:0-e

Research question Which subgroups of older people benefit most from vitamin D plus calcium?

Answer The supplements help to prevent falls in women but not men. Older women who are less active than average benefit most.

Why did the authors do the study? These authors had already shown that taking extra vitamin D (cholecalciferol) can reduce falls in older people by 20%. They wanted to find out whether the benefits were different for men, women, and other subgroups defined by physical activity or baseline serum concentration of 25-hydroxyvitamin D (25-hydroxycholecalciferol).

What did they do? They analysed data on falls from a previous randomised trial examining the effects …

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