Pale sulphonated shale oil reduces the size of venous ulcersBMJ 2006; 332 doi: https://doi.org/10.1136/bmj.332.7541.0-e (Published 09 March 2006) Cite this as: BMJ 2006;332:0-e
Research question Does pale sulphonated shale oil help to heal venous ulcers?
Answer Possibly. Pale shale oil helps to reduce the surface area of ulcers compared with compression alone but may not increase the chance of cure.
Why did the authors do the study? Pale sulphonated shale oil is an established treatment for inflammatory skin conditions such as psoriasis and eczema. Experiments in vitro and in vivo suggest the oil may have beneficial effects on wound healing. These authors wanted to test it formally as a topical treatment for venous ulcers. Venous ulcers are common and notoriously hard to treat.
What did they do? 119 German and Slovakian patients took part in …