Case reports of suspected adverse drug reactions: Case reports generate signals efficiently

doi:10.1136/bmj.332.7539.488-a

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Stefan Russmann, assistant professor of epidemiology (russmann@bu.edu)

Boston Collaborative Drug Surveillance Program, Boston University, Lexington, MA 02421, USA

EDITOR—Loke et al judge the value of case reports of suspected adverse drug reactions by the outcome measures of further formal validation and the incorporation into the product information.1 They conclude that such reports are of limited value.

The main sources of information or tools that are available for detecting and evaluating suspected adverse drug reactions are spontaneous reports, formal …