Women with diabetes are more at risk of fatal CHD than menBMJ 2006; 332 doi: http://dx.doi.org/10.1136/bmj.332.7533.0 (Published 12 January 2006) Cite this as: BMJ 2006;332:0
Type 2 diabetes increases the risk of dying from coronary heart disease (CHD) by up to 50% more in women than in men. Huxley and colleagues (p 73) carried out a meta-analysis of 37 prospective cohort studies that included more than 445 000 cases—four times as many as in previous reviews. In the 29 studies with multiple adjusted estimates, they found a relative risk (female:male) of 1.46 (95% CI 1.14 to 1.88). This may be a consequence of diabetes inducing a more adverse cardiovascular risk profile in women, combined with possible disparities in treatment of cardiovascular disease that favour men, say the authors.