ASCOT: a tale of two treatment regimens

BMJ 2005; 331 doi: https://doi.org/10.1136/bmj.331.7523.1022-a (Published 27 October 2005) Cite this as: BMJ 2005;331:1022

Is ASCOT-BPLA being hyped-up?

  1. Peter D Burrill, assistant director of public health (peter.burrill@chesterfieldpct.nhs.uk)
  1. Prescribing and Clinical Effectiveness, Chesterfield Primary Care Trust, Chesterfield S41 7PF

    EDITOR—McDougall et al discuss whether the small absolute differences in secondary outcomes seen in the ASCOT-BPLA study were attributable to the blood pressure differences achieved.1 They use the accompanying paper to argue that this was in fact not so.2

    However, the editorial that accompanies the ASCOT-BPLA study severely criticises this post-hoc analysis and considers that the 2.7 mm Hg …

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