Treatment for colorectal cancer should be based on genetic analysis

BMJ 2005; 331 doi: (Published 06 October 2005) Cite this as: BMJ 2005;331:799
  1. Claire Laurent
  1. Banbury

    Genetic analysis of colorectal cancers, rather than the current method of staging based on tumour anatomy and histology, would lead to better treatment regimes, a UK expert has proposed.

    Patrick Johnston, director of the cancer research centre at Queen's University, Belfast, said he believed that this “paradigm shift” in classifying tumours would improve estimation of prognosis and targeting of treatment. Speaking at the National Cancer Research Institute's conference in Birmingham this week, Professor Johnston argued that genetic profiling of tumours would allow clinicians to identify which patients with …

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