Calcium and vitamin D in preventing fractures: Data are not sufficient to show inefficacy

BMJ 2005; 331 doi: http://dx.doi.org/10.1136/bmj.331.7508.108-b (Published 7 July 2005)
Cite this as: BMJ 2005;331:108.3

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  1. Alex Vasquez, researcher (avasquez@bioticsresearch.com),
  2. John Cannell, president
  1. Biotics Research Corporation, 6801 Biotics Research Drive, Rosenberg, TX 77471, USA
  2. Vitamin D Council, 9100 San Gregorio Road, Atascadero, CA 93422, USA

    EDITOR—The study by Porthouse et al had two major design flaws.1 Firstly, the dose of vitamin D (800 IU per day) is subphysiological and therefore subtherapeutic. Secondly, their use of “self report” as a measure of compliance is unreliable.

    The dose of vitamin D at 800 IU daily was not determined …

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