Do selective serotonin reuptake inhibitors cause suicide?: Let's keep it in perspective

BMJ 2005; 330 doi: https://doi.org/10.1136/bmj.330.7500.1149-a (Published 12 May 2005) Cite this as: BMJ 2005;330:1149
  1. Isaac Sakinofsky, professor emeritus of psychiatry and public health sciences (isaac.sakinofsky@utoronto.ca),
  2. David L Streiner, director
  1. University of Toronto, CAMH-Clarke Site, 250 College Street, Toronto, ON, Canada M5T 1R8
  2. Kunin-Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Toronto, ON, Canada M6A 2E1

    EDITOR—The news media's preoccupation with whether antidepressants provoke suicidal behaviour has generated apprehension in the general public, and clinicians increasingly see patients resistant to taking selective serotonin reuptake inhibitors (SSRIs) even though they might benefit. The meta-analysis by Fergusson et al reported an excess of suicidal attempts with SSRIs v placebo and, initially, an alarming …

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