Fillers POEM

High dose statins lower C reactive protein

BMJ 2005; 330 doi: https://doi.org/10.1136/bmj.330.7497.0-e (Published 21 April 2005) Cite this as: BMJ 2005;330:0-e

Question Is a lower C reactive protein level after aggressive treatment with statins associated with a lower risk of recurrent coronary events?

Synopsis This is a post hoc analysis of a randomised trial that compared atorvastatin (Lipitor) 80 mg with pravastatin (Pravachol) 40 mg in 4162 patients with acute coronary syndrome. Of those, 3745 had low density lipoprotein (LDL) and C reactive protein (CRP) levels measured 30 days after hospital discharge. There was a linear relationship between the reduction in LDL and the risk of recurrent coronary events (cardiovascular death or non-fatal myocardial …

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