Non-specific effects of vaccinationBMJ 2005; 330 doi: http://dx.doi.org/10.1136/bmj.330.7495.844 (Published 07 April 2005) Cite this as: BMJ 2005;330:844
Vaccines have non-specific (heterologous) effects
- Frank Shann, director of intensive care ([email protected])
- Intensive Care Unit, Royal Children's Hospital, Parkville, VIC 3052, Australia
EDITOR—I support Fine's plea that we review the optimal immunisation schedule in developing countries using evidence from controlled trials rather than observational data.1 There are almost no controlled trials of the effect on mortality from all causes for any of the vaccines in the World Health Organization's schedule.
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