Fillers POEM

Two-drug hypertension regimen increases CVD mortality

BMJ 2005; 330 doi: (Published 17 March 2005) Cite this as: BMJ 2005;330:0-g

Question In the treatment of adults with hypertension, which other drug class added to diuretics most effectively reduces adverse cardiovascular events?

Synopsis Evidence shows that diuretics are equal to or superior to other agents as first line therapy for most patients with hypertension. More than one drug class, however, is frequently required to control hypertension. It is unclear which other drug classes, added to diuretics, optimally reduce adverse cardiovascular events. The investigators evaluated data obtained from women with hypertension enrolled …

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