This Week In The Bmj

CMF adjuvant chemotherapy for breast cancer achieves good long term results

BMJ 2005; 330 doi: http://dx.doi.org/10.1136/bmj.330.7485.0 (Published 27 January 2005) Cite this as: BMJ 2005;330:0

Adjuvant chemotherapy with cyclophosphamide, methotrexate, and fluorouracil (CMF) in patients with operable breast cancer benefits the long term prognosis. After median follow up of 28.5 years, Bonadonna and colleagues (p 217) report combined results of two previously published randomised controlled trials and one observational study. Their experience shows that CMF adjuvant chemotherapy at least halves patients' long term risk of relapse and death.



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