Fillers POEM

MRI is more accurate than mammogram in high risk patients

BMJ 2004; 329 doi: https://doi.org/10.1136/bmj.329.7476.0-e (Published 18 November 2004) Cite this as: BMJ 2004;329:0-e

Question Is magnetic resonance imaging more accurate than mammography in women at high risk of breast cancer?

Synopsis Magnetic resonance imaging (MRI) is an expensive test, but it may be more sensitive than mammography. The authors identified 1909 Dutch women aged 25-70 years with at least a 15% lifetime risk of breast cancer. This group included 358 carriers of mutations (largely BRCA1 and BRCA2) cancer, 1052 women with a 30% to 49% risk, and 499 with a 15% to 29% risk. Of these, 4.6% were lost to follow up, largely because they underwent prophylactic mastectomy. Another 4.7% refused MRI, usually because of claustrophobia. The mean age was 40 years; …

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