Study suggests hepatitis B vaccine increases risk of multiple sclerosis

BMJ 2004; 329 doi: http://dx.doi.org/10.1136/bmj.329.7468.703-a (Published 23 September 2004)
Cite this as: BMJ 2004;329:703.2

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  1. Owen Dyer
  1. London

    People vaccinated against hepatitis B triple their risk of developing multiple sclerosis over the following three years, a study in the current issue of the journal Neurology says (Neurology 2004;63:838-42).

    Researchers led by Dr Miguel Hernán of Harvard School of Public Health analysed the United Kingdom's general practice research database, which follows a representative sample of over three million British patients.

    They found 163 cases of multiple sclerosis that had first been diagnosed in the period 1993-2001 and which met the study's criteria on record keeping. Also analysed were 1604 matched controls who did not have multiple sclerosis.

    The report's key finding …

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