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  1. Munir Pirmohamed, professor of clinical pharmacology (munirp@liv.ac.uk),
  2. Sally James, research pharmacist,
  3. Shaun Meakin, research nurse,
  4. Chris Green, senior pharmacist
  1. Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool L69 3GE
  2. Wirral Hospitals NHS Trust, Wirral
  3. Royal Liverpool University Hospital, Liverpool L7 8XP

    EDITOR—The aim of our study was to elucidate the prevalence of adverse drug reactions associated with prescribed medicines. We agree with Williams and Taylor that alcohol and herbal medicines may be contributory factors but thought that our study could not accurately report on this aspect because of difficulties in verification of intake. More studies of a different design are needed in this area, and we are currently addressing the role of alcohol in warfarin related adverse drug reactions in a prospective study of 2000 patients using the AUDIT questionnaire,1 a validated instrument to assess alcohol misuse.

    With regard …

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