Medical journals don't publish trials on major global diseases

doi:10.1136/bmj.328.7452.1337-a

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David Spurgeon

Toronto

Few randomised controlled trials published in leading general medical journals address the major health problems that affect most of the world's poor people.

An analysis of trials published in six leading general medical journals in 1999 shows that only 14 of 90 trials (16%) that looked at at least one of the top 10 causes of the global burden of disease were highly relevant to international health, as assessed by World Health Organization criteria (CMAJ 2004;170:1673-7). Seven of the 35 most deadly and debilitating diseases were not studied in …