Higher numbers than previously predicted could be incubating vCJD
BMJ 2004; 328 doi: https://doi.org/10.1136/bmj.328.7451.1279 (Published 27 May 2004) Cite this as: BMJ 2004;328:1279- Zosia Kmietowicz
- London
More people in the United Kingdom than previously thought could be incubating the variant Creutzfeldt-Jakob disease (vCJD), suggests new research.
An analysis of nearly 13 000 anonymised appendix and tonsil samples has found that prion proteins associated with vCJD had accumulated in three of them.
However, only one of the samples showed a pattern of prion accumulation that resembled that seen in tissue of known vCJD cases. The other two had different patterns of accumulation and their significance is uncertain, although they cannot be dismissed as unimportant, say researchers.
Extrapolating …
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