NICE gives guidance on use of new antiepileptic drugs in children

BMJ 2004; 328 doi: (Published 06 May 2004) Cite this as: BMJ 2004;328:1093
  1. Susan Mayor
  1. London

    Newer antiepileptic drugs should be considered for treating epilepsy in children who have not benefited from older drugs, or where use of the older drugs is unsuitable, says guidance issued this week to the NHS in England and Wales.

    The National Institute for Clinical Excellence (NICE) recommends that the newer antiepileptic drugs—gabapentin, lamotrigine, oxcarbazepine, tiagabine, topiramate, and vigabatrin (as an adjunctive treatment for partial seizures)—be used, within their licensed indications, for managing epilepsy in children who have not benefited from treatment with the older antiepileptic drugs, such as carbamazepine and sodium valproate.

    The …

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