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  1. Caroline White
  1. London

    Hormone replacement therapy (HRT) should not be used to prevent chronic disease in women who have gone through the menopause. This is the conclusion from the latest trial in the US women's health initiative (WHI) study, published this week in JAMA (2004;291: 1701-12).

    But HRT does have a role in the short term relief of menopausal symptoms, concludes an accompanying editorial (JAMA 2004;291: 1769-71).

    The study, a randomised, double blind, placebo controlled trial of unopposed oestrogen—0.625 …

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