Adding amynoglycoside to βlactam does not improve results

BMJ 2004; 328 doi: (Published 08 April 2004) Cite this as: BMJ 2004;328:884

In this summary in This Week in the BMJ (of the paper by Mical Paul and colleagues, “βlactam monotherapy versus β lactam-aminoglycoside combination therapy for sepsis in immunocompetent patients: systematic review and meta-analysis of randomised trials,” pp 668-672) a vital word was wrong. The first sentence should read: “In patients with sepsis but without [not “with“] neutropenia, mortality is no different whether βlactams and aminoglycosides are used together or β lactams are used alone, although the risk of adverse effects is increased with βlactams and aminoglycosides.” And, as you will have noticed, we also slipped up on the spelling of aminoglycoside in the summary's title.


View Abstract