Treating major depression in children and adolescents

doi:10.1136/bmj.328.7438.524-b

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Research is needed into safer and more effective drugs

Macey L Murray, research fellow (macey.murray@ulsop.ac.uk),
Ian C K Wong, director,
Corinne S de Vries, senior lecturer

Centre for Paediatric Pharmacy Research, School of Pharmacy, University of London, London WC1N 1AX
Department of Pharmacoepidemiology, Postgraduate Medical School, University of Surrey, Guildford GU2 7DJ

EDITOR—We report our preliminary findings on prescribing of antidepressants in general practice, in response to the recommendation by the regulatory agency for medicines and healthcare products to withdraw selective serotonin reuptake inhibitors from use in paediatric depression.1 2

We used the general practice research database to analyse use between 1 January 1992 and 31 December 2001 (88 522 prescriptions issued to 23 999 …