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Wagner somehow believe in the medieval concept of
love potions as shown in the opera Siegfried from the
Ring of the Nibelung, around 10 years after Tristan. He
used it again in Siegfried, with immediate effect in his
affections and resulting in profound selective amnesia,
but no other clinical features.
It might be interesting to note that almost all symptoms
described by Wagner and interpreted by Weitz could also be elicited by a
methylenedioxymethamphetamine (MDMA, a.k.a. Ecstasy) intoxication.
Immediate strong and enduring love is more typical for a MDMA rather
than a Solanaceae intoxication.
'Love Potion #9' is one street name for MDMA, referring to its
empathogenic/entactogenic effects with a heightened sense of closeness to
other people [CMAJ 2001;165(7):917-28].
Maybe Tristan and Isolde have been on natural(?) ecstasy.