- Georgia Duckworth, head (georgia.duckworth@hpa.org.uk)
- Division of Healthcare Associated Infection and Antimicrobial Resistance, Communicable Disease Surveillance Centre, Health Protection Agency, London NW9 5EQ
Time to return to more stringent methods of control in the United Kingdom?
Methicillin resistant Staphylococcus aureus (MRSA) is a major cause of hospital acquired infection worldwide, posing a growing threat to public health. It belongs to a species of ubiquitous and versatile organisms that are continually adapting to new antimicrobial and environmental challenges, often through gene transfers even from distantly related organisms such as vertebrates. Why is MRSA important? Some strains are eminently transmissible, resulting in large numbers of infections in hospitals. Bacteraemia data for England and Wales show that MRSA as a proportion of total Staphylococcus aureus bacteraemias rose from under 2% in 1990 to 42% in 20001 2—one of the highest reported rates in Europe.
Methicillin resistance was first reported in 1961 shortly after the introduction of methicillin (similar to flucloxacillin), the first penicillin resistant to destruction by staphylococcal β-lactamase. The discovery of methicillin was an important development as many hospital strains of S aureus had become penicillin resistant in the 1950s through the production of β-lactamase.w1 Some European countries experienced problems with MRSA in the 1960s, but this was followed by …
Sign in
Article access
Article access for 1 day
Purchase this article for £20 $30 €32*
The PDF version can be downloaded as your personal record







CiteULike
Connotea
Del.icio.us
Digg
Facebook
Mendeley
Reddit
Technorati
Twitter
Stumbleupon
Rapid responses
Latest Responses
Re: Ventilator associated pneumonia
Published 30 May 2012
Re: Restless legs syndrome
Published 30 May 2012
Author's reply
Published 30 May 2012
Re: Full access to trial data holds many benefits and a few pitfalls, conference hears
Published 30 May 2012
Restless Legs Syndrome: Fact or Fiction
Published 30 May 2012
Most responses
Venous thrombosis in users of non-oral hormonal contraception: follow-up study, Denmark 2001-10 (12 responses)
Published 10 May 2012 - 23:32
The psychiatric oligarchs who medicalise normality (9 responses)
Published 2 May 2012 - 15:42
Are doctors justified in taking industrial action in defence of their pensions? No (8 responses)
Published 8 May 2012 - 12:21
Are doctors justified in taking industrial action in defence of their pensions? Yes (8 responses)
Published 8 May 2012 - 12:21
The hardest thing: admitting error (7 responses)
Published 2 May 2012 - 12:27