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Antibiotics are no better than placebo for symptoms of sinusitis

BMJ 2003; 327 doi: (Published 06 November 2003) Cite this as: BMJ 2003;327:0-h

Question Is co-amoxiclav effective in treating acute sinusitis diagnosed in general practice?

Synopsis Sinusitis is a tricky diagnosis; just distinguishing sinus infection from rhinitis is difficult. Moreover, a good proportion of the patients who have sinusitis have a viral infection. This randomised controlled trial (double blind) study evaluated the role of antibiotics in 252 adults with a clinical diagnosis of rhinosinusitis. The patients had a history of repeated purulent …

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