Bmj Usa: Letter

RAPID RESPONSES FROM BMJ.COM: Anti-inflammatory end points

BMJ 2003; 327 doi: https://doi.org/10.1136/bmjusa.01100003 (Published 19 November 2003) Cite this as: BMJ 2003;327:E73
  1. Brian J Lipworth (b.j.lipworth@dundee.ac.uk),
  2. Stephen Fowler,
  3. Graeme Currie,
  4. Andrew Wilson
  1. Asthma and Allergy Research Group, Ninewells University Hospital, Dundee, UK
  2. Wellington Asthma Research Group, Wellington, New Zealand

    This article originally appeared in BMJ USA

    Editor—In the meta-analysis by Holt et al, none of the studies measured airway inflammation or hyperresponsiveness, which are fundamental to asthma pathophysiology. Studies with fluticasone and other inhaled corticosteroids have shown a steeper dose response for effects on airway hyperresponsiveness than for other outcomes, such as lung function, …

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