Filler POEM

Paroxetine may help with hot flushes

BMJ 2003; 327 doi: (Published 02 October 2003) Cite this as: BMJ 2003;327:0-f

Question Is paroxetine useful in the treatment of menopausal hot flushes?

Synopsis Many women—and their clinicians—are now reluctant to use hormone replacement therapy. As a result, other effective alternative treatments for menopausal symptoms, especially hot flushes, are needed. A total of 165 menopausal women, 18 years or older, experiencing significant hot flushes were enrolled. After a one week placebo run-in phase to screen out high responders to placebo, participants were randomised (uncertain concealment of …

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