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Kaposi's sarcoma virus implicated in primary pulmonary hypertension

BMJ 2003; 327 doi: https://doi.org/10.1136/bmj.327.7417.702-e (Published 25 September 2003) Cite this as: BMJ 2003;327:702
  1. Deborah Josefson
  1. Nebraska

    The virus that is associated with Kaposi's sarcoma, human herpesvirus 8, may be involved in the genesis of primary pulmonary hypertension, a new study says (New England Journal of Medicine 2003;349:1113-22).

    Primary pulmonary hypertension is a rare lung condition, affecting 2-3 people in a million, in which progressive dyspnoea and right heart failure occur secondary to an abnormal proliferation of endothelial cells in the blood vessels of the lungs. The diagnosis is made through exclusion, and the causes of the disease have been obscure.

    Despite the association of …

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