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Hormone treatment increases breast cancer risk, study shows

BMJ 2003; 327 doi: https://doi.org/10.1136/bmj.327.7411.359 (Published 14 August 2003) Cite this as: BMJ 2003;327:359
  1. Susan Mayor
  1. London

    Long term use of combined hormone replacement therapy (HRT) doubles the risk of breast cancer, according to a major epidemiological study published last week that showed for the first time the higher risk with combined oestrogen and progestogen treatment.

    From 1996 to 2001 the million women study recruited 1 084 110 women in the United Kingdom aged 50-64 years. When they were invited to attend for routine mammography the women were asked to complete a questionnaire that included questions about their use of HRT. They were then …

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