Fillers POEM

Oral clindamycin for asymptomatic bacterial vaginosis in early pregnancy reduces premature births

BMJ 2003; 327 doi: https://doi.org/10.1136/bmj.327.7407.0-e (Published 17 July 2003) Cite this as: BMJ 2003;327:0-e

Question Does treatment with oral clindamycin for bacterial vaginosis before 22 weeks' gestation lead to decreased premature births and late miscarriages?

Synopsis Previous studies of screening for bacterial vaginosis in pregnancy performed the screening late in the second trimester and treated bacterial vaginosis with metronidazole. In this randomised controlled double blinded trial, a general population of 6120 asymptomatic pregnant women in the United Kingdom was screened in antenatal outpatients for bacterial vaginosis by using Gram stain and Nugent scoring (0-10), and 494 (8.1%) women positive for bacterial vaginosis with a Nugent score …

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