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The optimal serum digoxin concentration in men with stable heart failure in sinus rhythm is 0.5 to 0.8 ng/ml

BMJ 2003; 326 doi: (Published 15 May 2003) Cite this as: BMJ 2003;326:0-f

Question What is the optimal serum digoxin concentration for men with heart failure?

Synopsis Recent findings from the Digitalis Investigation Group (DIG) trial suggest strongly that only men with heart failure benefit from treatment with digoxin. In this post hoc analysis of data from the original three year randomised controlled double blinded trial (conducted in outpatient clinics), the authors assessed variations in serum digoxin concentration (SDC) and their associations …

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