Parametric survival models may be more accurate than Kaplan-Meier estimates

BMJ 2003; 326 doi: https://doi.org/10.1136/bmj.326.7393.822 (Published 12 April 2003) Cite this as: BMJ 2003;326:822
  1. Margaret May, statistician,
  2. Jonathan Sterne, reader in medical statistics and epidemiology,
  3. Matthias Egger, professor of epidemiology
  1. Department of Social Medicine, University of Bristol, Bristol BS6 2PR
  2. Department of Social and Preventive Medicine, University of Bern, Switzerland

    EDITOR—Lundin et al use Kaplan-Meier estimates of survival probabilities in their system for survival estimation in breast cancer (Finprog study, http://finprog.primed.info).1 They claim that researchers can obtain survival estimates based on actual data, rather than inferential estimates generated by a regression formula. However, any regression formula is based on actual data. More importantly, survival estimates from a regression model may be substantially more precise than Kaplan-Meier estimates …

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