Treatment slows moderate to severe Alzheimer's diseaseBMJ 2003; 326 doi: https://doi.org/10.1136/bmj.326.7393.784 (Published 12 April 2003) Cite this as: BMJ 2003;326:784
- Janice Hopkins Tanne
- New York
For the first time, a treatment has been shown to slow the mental and physical decline of patients with moderate to severe Alzheimer's disease by about six months (New England Journal of Medicine 2003;348:1333-41).
The US researchers conducted a double blind, randomised controlled trial of memantine. The drug had been marketed in Germany by Merz Pharmaceuticals for a decade for Parkinson's disease and other neurodegenerative diseases before being licensed in May 2002 by the European Union …