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HRT and antioxidant vitamins increase the risk of cardiovascular disease

BMJ 2003; 326 doi: https://doi.org/10.1136/bmj.326.7385.0/f (Published 15 February 2003) Cite this as: BMJ 2003;326:f

Question Are hormone replacement therapy (HRT) and antioxidant vitamins useful for the secondary prevention of coronary events in postmenopausal women?

Synopsis Until recently, both hormone replacement therapy and antioxidant vitamins were widely used for secondary prevention of coronary events in postmenopausal women with established cardiovascular disease. To assess the effectiveness of these treatments, 423 postmenopausal women with at least one 15-75% coronary artery stenosis at baseline were identified. Patients were …

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