Adjuvant chemotherapy improves survival in early ovarian cancer

BMJ 2003; 326 doi: (Published 25 January 2003) Cite this as: BMJ 2003;326:181
  1. Susan Mayor
  1. London

    Immediate treatment with chemotherapy after surgery significantly improves survival and reduces recurrence of cancer in women with early ovarian cancer, show two major international trials published this week.

    The first trial, the international collaborative ovarian neoplasm trial 1, randomly assigned 477 women with early stage epithelial ovarian cancer to receive platinum based adjuvant chemotherapy immediately after surgery or to receive no adjuvant chemotherapy until clinically indicated when further symptoms developed (Journal of the National Cancer Institute 2003; 95:125-32). It is the largest clinical trial to be carried out in …

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