Vaccine induced protection against hepatitis B

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Pierre Van Damme, professor (pierre.vandamme@ua.ac.be),
Jangu E Banatvala, emeritus professor of clinical virology

Department of Epidemiology and Social Medicine, University of Antwerp, Universiteitsplein, 1, B-2610 Wilrijk, Belgium
Guy's, King's College, and St Thomas's School of Medicine and Dentistry, London

EDITOR—Whittle et al report one of the few long term follow up studies of children vaccinated against hepatitis B.1 The reported reduction in the rate of carriers of hepatitis B surface antigen in two villages in the Gambia, from 13% to 1% and from 35% to 2% respectively, represents a major achievement in public health.

We are concerned, however, that those who are influential in deciding policy of hepatitis B vaccination may not appreciate that relevant information is missing in …