Metronidazole is used for antibiotic associated diarrhoea in pregnancy in UKBMJ 2002; 325 doi: https://doi.org/10.1136/bmj.325.7369.903 (Published 19 October 2002) Cite this as: BMJ 2002;325:903
- Scott Pegler, medicines information pharmacist. (firstname.lastname@example.org),
- Patricia McElhatton, head.
- Morriston Hospital, Swansea NHS Trust, Swansea SA6 6NL
- National Teratology Information Service, Regional Drug and Therapeutics Centre, Wolfson Unit, Newcastle upon Tyne NE2 4HH
EDITOR —Barbut and Meynard quote US guidance when recommending vancomycin as first line treatment for antibiotic associated diarrhoea in pregnancy.1
In the United Kingdom guidance issued by the medicines information centres and the National Teratology Information Service recommends metronidazole rather than oral vancomycin after a careful risk assessment of each drug.
Vancomycin is poorly absorbed from normal, intact gastrointestinal mucosa, but an inflammatory bowel process can …