Clinical Review

Vulvovaginal candidiasis

BMJ 2002; 325 doi: (Published 14 September 2002) Cite this as: BMJ 2002;325:586

This article has a correction. Please see:

  1. Jeanne Marrazzo, medical director.
  1. Seattle STD/HIV Prevention and Training Center, Harborview Medical Center, Box 359931, Seattle, WA 98104, USA

    DefinitionVulvovaginal candidiasis is symptomatic vaginitis (inflammation of the vagina), which often involves the vulva, caused by infection with a Candida yeast. Predominant symptoms are vulvar itching and abnormal vaginal discharge (which may be minimal, a “cheese like” material, or a watery secretion). Differentiation from other forms of vaginitis requires the presence of yeast on microscopy of vaginal fluid. The definition of recurrent vulvovaginal candidiasis varies among RCTs, but is commonly defined as four or more symptomatic episodes a year. This summary excludes studies of asymptomatic women with vaginal colonisation by Candida species.

    • What are the effects of treatments for symptomatic vulvovaginal candidiasis in non-pregnant women?

    • Beneficial

    Intravaginal imidazoles

    RCTs have found that intravaginal imidazoles (e.g. clotrimazole) …

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